Netflix Opioid Crisis Series ‘Painkiller’ Cast and Character Guide

Painkiller, Netflix’s anticipated and upcoming new limited series about the U.S. opioid crisis, releasing Aug. 10 from the EP team of Eric Newman (NarcosTrue Story) and director Pete Berg (Friday Night LightsSpenser Confidential) is inspired by real events amid the country’s opioid crisis and features a cast including Uzo Aduba, Matthew Broderick, Taylor Kitsch (marking a FNL reunion with Berg), Dina Shihabi, West Duchovny and John Rothman.

Clark Gregg, Jack Mulhern, Sam Anderson, Ana Cruz Kayne, Brian Markinson, Noah Harpster, John Ales, Johnny Sneed, Tyler Ritter and Carolina Bartczak guest star.

Learn more about the actors who play the perpetrators, victims, and truth-seekers whose lives are altered by the introduction of OxyContin in the series below. While some characters — like the Sacklers and US Attorney John Brownlee — are inspired by real people, others are fictional, representing the experiences of so many.

Uzo Aduba as Edie Flowers

Edie Flowers

Edie Flowers

Edie Flowers is a no-nonsense lawyer working for the US attorney’s office in Roanoke who’s investigating the new drug OxyContin. She attempts to bring a case against Purdue Pharma, the company that makes OxyContin and is widely blamed for creating the opioid epidemic in America.

Aduba starred in Orange Is the New Black, In Treatment, Mrs. America, Steven Universe, Candy Jar, Miss Virginia, Really Love, Solos, National Champions, Showing Roots, Lightyear, Beats, American Pastoral, and Talluah

Matthew Broderick as Richard Sackler

Richard Sackler

Richard Sackler

Richard Sackler is the scion of the billionaire family and a senior executive at Purdue Pharma. He’s the nephew of Arthur Sackler, the founder of Purdue. After Arthur passes away and saddles his family with debt, it’s Richard’s idea to make opiates the company’s profit engine.

Matthew Broderick starred in Ferris Bueller’s Day Off, WarGames, Election, The Lion King, The Producers, Glory, The Freshman, The Cable Guy, The Tale of Despereaux, The Stepford Wives, Godzilla, Daybreak, BoJack Horseman, and Inspector Gadget

Taylor Kitsch as Glen Kryger

Glen Kryger

Glen Kryger

Glen Kryger is a hardworking family man and small business owner whose life is upended after he suffers an injury at work and his doctor prescribes him OxyContin.

Taylor Kitsch starred in Friday Night Lights, True Detective, The Terminal List, The Defeated, The Normal Heart, Waco, 21 Bridges, American Assassin, Savages, John Carter, The Covenant, and X-Men Origins: Wolverine

West Duchovny as Shannon Schaeffer

Shannon Schaeffer

Shannon Schaeffer

Shannon Schaeffer is an ex-college athlete who’s desperate to leave her parents’ home in Ohio. She finds a job as a new recruit to the Purdue sales team. As her role becomes increasingly lucrative, her conscience comes into play.

West Duchovny starred in Saint X, The Magicians, Linoleum, A Mouthful of Air, Vegas High, The Report, Sick, and The X-Files

Carolina Bartczak as Lily Kryger

Lily Kryger

Lily Kryger

Lily Kryger is Glen’s wife. She is very much in love with him and tries her best to support her husband after his injury. But she is pushed to the brink by his increasingly dangerous and harmful behaviors.

Carolina Bartczak starred in X-Men: Apocalypse, Moonfall, Brick Mansions, An Audience of Chairs, The Bold Type, Business Ethics, White Lie, Most Dangerous Game, Within These Walls, Hall, Death of a Ladies’ Man, Be Mine, Valentine, A Charming Valentine, Christmas in Love, The Mysteries of Alfred Hedgehog, Covert Affairs, The Listener, Karma’s a B*tch!, The Secret Life of Marilyn Monroe, and Air Crash Investigation

Jack Mulhern as Tyler Kryger

Tyler Kryger

Tyler Kryger

Tyler Kryger is Glen’s 17-year-old stepson who is prone to angst and rebellion. He struggles with guilt because Glen’s accident happened while they were arguing at their family-owned tire shop.

Tyler Kryger starred in The SocietyMare of EasttownWu-Tang: An American SagaUnconformity, and Odd Man Rush

Dina Shihabi as Britt Hufford

Britt Hufford

Britt Hufford

Britt Hufford is a veteran sales rep for Purdue who mentors Shannon. Beneath her unflinching devotion to the company lies deep insecurity.

Dina Shihabi starred in Altered Carbon, Archive 81Tom Clancy’s Jack RyanDaredevilBKPIGhosts of BeirutAgent StokerMadam SecretaryMVPRamy, and Catching Dust

Clark Gregg as Arthur Sackler

Arthur Sackler

Arthur Sackler

Arthur Sackler is the patriarch of the Sackler family and founder of Purdue. He is the one who realized that the big money in medicine was in sales and marketing. He appears to Richard as an apparition throughout the series to guide his nephew in his handling of the family legacy.

Clark Gregg starred in The Marvel Cinematic Universe (films and series including Iron ManAgents of S.H.I.E.L.D.ThorThe AvengersCaptain MarvelUltimate Spider-Man, and What If.. ?), The New Adventures of Old ChristineMuch Ado About Nothing, Very Good GirlsThe To Do ListLabor DayBrightest Star, Live by NightSpinning ManThe ConnersMoxieBeing the RicardosRun Sweetheart RunHow I Met Your FatherFlorida ManThe West WingHoot, In the Land of WomenChoke500 Days of SummerMr. Popper’s PenguinsAs the World Turns, Clear and Present DangerThe Usual SuspectsSports Night, Sex and the CityThe Practice, and Will & Grace

John Rothman as Mortimer Sackler

John Rothman as Mortimer Sackler (left) in Season 1 of Painkiller

John Rothman as Mortimer Sackler (left) in Season 1 of Painkiller

Mortimer Sackler is the co-owner of Purdue Pharma and Richard Sackler’s uncle.

John Rothman starred in The Devil Wears PradaGhostbustersBigTaxiGettysburgJingle All the WayPicture PerfectPollockSay It Isn’t SoWelcome to MooseportPrimeUnited 93One MississippiThe ReportBombshell, and Enchanted

Tyler Ritter as Us Attorney John Brownlee

John Brownlee

John Brownlee

US Attorney John Brownlee is Edie Flowers’ new boss, who is a clean-cut straight-shooter. She works hard to convince him to take down Purdue in pursuit of true justice.

Tyler Ritter starred in Merry Happy WhateverThe McCarthysArrowAgents of S.H.I.E.L.D.Modern FamilyGrey’s AnatomyYoung & HungryNCISLoosely Exactly NicoleHot in ClevelandThe Good Doctor, and An Evergreen Christmas

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